The station is named after the nearby Calzada de los Misterios, an avenue with multiple hermitages depicting the Mysteries of the Rosary.
Misterios is an underground metro station along Avenida Río Consulado, in northeastern Mexico City.
Misterios metro station has two exits that lead to Avenida Río Consulado and Calle Constantino.
Calzada de los Misterios has fifteen hermitages, built in the 17th century, which reference and illustrate the Mysteries of the Rosary.
The plan for Line 8 was later modified to run from Indios Verdes to Constitución de 1917 station, still stopping at Misterios.
[23] A train window was ejected in the tunnel between Valle Gómez, causing a short circuit on station 21 February 2021.