SH 224 heads south along four-lane undivided Broadway through the unincorporated area of Twin Lakes.

SH 224 heads east on 70th Avenue as a four-lane divided highway that has a partial interchange with I-25 allowing access to I-25 to and from Denver; the route also intersects a ramp toward Denver for the I-25 express lanes.

[2] SH 224 continues into unincorporated Welby and curves northeast parallel to Clear Creek, reduces to two lanes, and passes under I-270 with no access.

East of its bridge across the South Platte River north of its confluence with Clear Creek, SH 224 expands to a four-lane divided highway and crosses over the Regional Transportation District (RTD) N line rail line within its partial interchange with I-76, which allows access to I-76 to and from Denver.

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