The route then turns onto cherry Street in Fruita where it junctions with Interstate 70 (I-70).

There, it traverses the suburban area as Broadway Road, passing the Colorado National Monument on the south side of the highway.

As SH 340 travels eastward, it enters Downtown Grand Junction, meeting again with the Colorado River and passing over the Riverside Parkway.

The route was defined in 1939, when it moved along its current alignment but continued to US 6 in Palisade.

Media related to Colorado State Highway 340 at Wikimedia Commons