[3] Unit coal trains are very common on the Columbus Subdivision, but a large variety of commodities travel along the line.

[3] Direct Traffic Control is also used along the subdivision to separate trains, with a large number of DTC Blocks named after nearby municipalities.

Nonetheless, the line also carried passenger traffic and reported 25M passenger-miles and 2.6B freight ton-miles per year.

Passenger traffic also began to dwindle as personal automobiles and Interstate Highways proliferated, forcing the railroad to focus more on freight movements and remove most small, local depots from service.

The southern, Columbus–Fostoria portion kept its name, while the northern track towards Toledo was renamed the Pemberville Subdivision and placed into CSX's Great Lakes operating division.