[1] Members of this family are characterized by possession of one or paired blade-like or knob-like projections on a few to many of the outer segments of the oral pinnules (the side branches closest to the base of the arms) that together form structures called combs.

In adults of most species, the mouth is offset from the center of the oral surface, often near the margin, and the anus lies centrally.

Comasterids are also unique among feather stars in other respects: some species in several genera have the centrodorsal, the aboral skeletal plate, reduced and bearing few or no anchoring hook-like cirri; whereas all other feather stars have symmetrical rays, many reef-dwelling species that live semi-cryptically exhibit a secondary bilateral symmetry in addition to the displaced mouth; arms that arise on one or more rays on the side closest to the mouth are longer than those on the other side.

They are the ones that extend from the protective crevice and are the primary food collecting structures.

Shorter arms opposite the long ones often have better developed gonads and may even lack food-collecting ambulacral grooves.