It can be found in Combretum afrum, the Eastern Cape South African Bushwillow tree.

[1] It is an antiangiogenic agent acting by destabilizing tubulin, which induces cell apoptosis of proliferating endothelial cells.

[1] Currently designated an orphan drug by the FDA, combretastatin A1 diphosphate (OXi4503 or CA1P) is in Phase I clinical trials for relapsed and refractory acute myeloid leukemia and myelodysplastic syndrome.

[2] This article about an aromatic compound is a stub.

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