Comesperma integerrimum is a twining shrub or climber in the family Polygalaceae.

[4] The species was first formally described as Comesperma integerrima by the botanist Stephan Endlicher in Enumeratio plantarum quas in Novae Hollandiae ora austro-occidentali ad fluvium Cygnorum et in sinu Regis Georgii collegit Carolus Liber Baro de Hügel in 1837, from a specimen collected by Charles von Hügel at King George Sound (Western Australia).

[1][2] The species occurs in the states of New South Wales and Western Australia.

[3][5] Comesperma integerrimum is a climber growing from 30 cm to 8 m high,[4] with sparsely branched, ridged stems with appressed hairs between the ridges.

The inflorescences are terminal on short side branches on stalks about 3.5 mm long.