[2] During the Ancien Régime, Comologno belonged to the Squadra of Crana, which together with the other villages of the valley (with the exception of Auressio) formed the medieval municipality of Onsernone.
With the emergence and development of rye straw processing in the 19th century, the population of Comologno increased rapidly.
Another notable mansion is the Palazzo (or Castello) della Barca which was acquired in the 1930s by Vladimir Rosenbaum for his wife Aline Valangin, a writer and artist.
It soon became a haven for artists and well-known anti-fascists, including Ignazio Silone, Ernesto Rossi, Kurt Tucholsky, Hans Marchwitza, Ernesto Bonaiuti, Max Terpis, Elias Canetti, Wladimir Vogel and Jean-Paul Samson.
Since the early 1970s, at the suggestion of the Associazione Amici di Comologno, various artists have decorated houses in the village with frescos.