Conjugated linoleic acid

[citation needed] CLA and some trans isomers of oleic acid are produced by microorganisms in the rumens of ruminants.

[citation needed] However, this bioconversion may not occur at any significant level in those with a digestive disease, gluten sensitivity, or dysbiosis.

[9][10][11][12] CLA is marketed in dietary supplement form for its supposed anti-cancer benefit (for which there is no strong evidence or known mechanism, and very few studies conducted so far)[13] and as a bodybuilding aid.

[14] Likewise, there is insufficient evidence that CLA has a useful benefit for overweight or obese people as it has no long-term effect on body composition.

[16] Food products from grass-fed ruminants (e.g. mutton and beef) are good sources of CLA and contain much more of it than those from grain-fed animals.