[5][6] As a sophomore in 2016, he started all 59 games and saw time at catcher, third base, and the outfield; for the season, Wong had a slash line of .304/.415/.435 with five home runs and 30 RBIs, earning all-conference first-team honors in the American Athletic Conference.

[7][8] He returned to the Cape Cod League that summer, playing 41 games with the Bourne Braves, batting .313 with three home runs and earning all-star honors.

In 2018, Wong played for the Rancho Cucamonga Quakes of the Class A-Advanced California League (with whom he earned all-star honors), slashing .269/.350/.480 with 19 home runs and 60 RBIs over 102 games.

[14][15][16] Wong returned to the Quakes to begin 2019, earning all-star honors for the second straight year, before being promoted to the Tulsa Drillers of the Double-A Texas League in July.

[19] On February 10, 2020, Wong was traded to the Boston Red Sox along with Jeter Downs and Alex Verdugo in exchange for Mookie Betts, David Price and cash considerations.

[23] On June 22, he was promoted to the major leagues for the first time and made his major-league debut against the Tampa Bay Rays as a pinch runner in extra innings.

[33] The next evening, Wong hit a sacrifice fly to drive in the winning run in a 2–1 victory over the Toronto Blue Jays.

[36] He sustained a hand injury on July 29 when he was hit by a pitch in a Triple-A contest, causing him to miss multiple games.