Conophytum wettsteinii is a species of flowering plant in the genus Conophytum, native to the northwest Cape Provinces of South Africa.

[3] It is known to grow in rocky regions, often associated with Crassula elegans.

C. wettsteinii is a small groundcover species, which appears stemless with fused leaf-pairs having a obconical shape.

This plant relies on winter rains and is mainly dormant in summer months.

[4] It has gained the Royal Horticultural Society's Award of Garden Merit.