Her marriage into the House of Medici provided her husband's family with much needed nobility, prestige, and military support as they established their power in Florence.

[1] Additionally, Contessina agreed to take charge of Cosimo's illegitimate son by a Circassian slave, Carlo de' Medici.

[7] She had a good relationship with her daughter-in-law Lucrezia Tornabuoni, and she lived with her and her son Piero after her husband's death.

[10] Her grandson Lorenzo named one of his daughters Contessina de' Medici in honor of her.

Contessina is portrayed by Annabel Scholey in the 2016 television series Medici: Masters of Florence.