He immediately began the task of hauling the noble train of artillery from captured Fort Ticonderoga to Cambridge.

The Fortification of Dorchester Heights in March 1776, in which Knox's artillery regiment was a critical component, hastened the end of the Siege of Boston.

Knox's regiment participated in the New York and New Jersey Campaign during the summer and fall of 1776.

The actions in which cannons were employed were the battles of Long Island, White Plains, and Fort Washington.

Knox's guns were crucial in winning the Battle of Trenton in late December 1776.