Father Clement Charles Grenier from Penang, following a request from the Catholic families for a girls school in Taiping.

On 28 July 1902, primary classes were started in the new classrooms at the Convent Kelian Pauh.

In December 1902, four candidates from the school set out for Penang to sit for the preliminary examination of the forerunner of the Junior Cambridge Certificate.

In 1900, Mother Clothide became the first headmistress for an Indian girls school; known as St. Theresa Convent with 26 students.

The present buildings for the secondary school date back to 1938, situated next to the St. Louis Church.

On 10 January 2010, it was reported by the Malaysian Insider that Molotov cocktails were found near the school compounds.