Sekolah Menengah Sains Teluk Intan (English: Teluk Intan Science Secondary School; abbreviated SEMESTI) is a fully residential school in Malaysia.

This school is located 13 miles from Teluk Intan and has an area of 21.5 hectares.

The early work on building this science school started in September 1980.

The first principal was Tuan Haji Noor bin Bakar PJK, who took up his post on 1 February 1984.

[1] Now with the current headboy, Aqiel Wazif bin Shahril SEMESTI can reach its former glory.