Convent of the Sacred Heart is an independent Catholic all-girls' school in Manhattan, New York City.

Burden House, both of which are New York City-Designated Landmarks, and are listed on the National Register of Historic Places.

The school was originally housed in a Manhattan brownstone on Madison Avenue at East 54th Street.

By the 1930s, the school had outgrown its Madison Avenue space and moved into the Otto H. Kahn House.

In September 2008, the school purchased a facility located at 406 East 91st Street and created a new sports center.