Corilagin

Corilagin was first isolated in 1951 from Dividivi extract and from Caesalpinia coriaria,[1][2] hence the name of the molecule.

It can also be found in Alchornea glandulosa and in the leaves of Punica granatum (pomegranate).

[3] It is a weak carbonic anhydrase inhibitor.

[4] Ellagic acid and corilagin inhibit TGF-β1–dependent EMT and has been shown to attenuate fibrogenesis in a mouse model.

[5] Fibrosis is also indicated in many health conditions, including skin aging and MRSA susceptibility.

Chemical structure of corilagin
Chemical structure of corilagin