Raven-Symoné was offered the spin-off, but she declined it, therefore Disney Channel decided to give it to Kyle Massey.

For example, "We Built This Kitty on Rock and Roll" comes from "We Built This City", "Mall of Confusion" from "Ball of Confusion", "Smells Like School Spirit" from "Smells Like Teen Spirit", and "Ain't Miss Bahavian" from "Ain't Misbehavin'".

The theme song to Cory in the House was written and produced by Matthew Gerrard and Robbie Nevil, and performed by Kyle Massey, Maiara Walsh, and Jason Dolley (though the closing credits of the show credit the performance of the theme song only to Massey).

An alternate theme song, "Rollin' to D.C.", is also sung by Massey and Walsh and was used in the music video to promote the series.

The show was initially planned to be added to the ABC Kids lineup in the fall of 2007, but it was scrapped later on.