Corynebacterium amycolatum is a gram-positive, non-spore-forming, aerobic or facultatively anaerobic bacillus capable of fermentation [1] with propionic acid as the major end product of its glucose metabolism.

[3] C. amycolatum has been shown to cause pneumonia, peritonitis, empyema, infectious endocarditis, and fatal sepsis, most of which occur as nosocomial infections.

Corynebacterium endocarditis usually infects the left side of the heart in males, though C. amycolatum has shown a predilection for women.

[4] While cases of disease have been small in number, this underreporting could be due to misdiagnosis of C. amycolatum as C. xerosis, which is a known human pathogen.

Various strains tested have shown resistance to beta lactam antibiotics, lincosamides, macrolides, and quinolones.