Cospin is a serine protease inhibitor from the mushroom species Coprinopsis cinerea in the phylum Basidiomycota.
It has similar biochemical properties to other well characterized fungal serine protease inhibitors of family I66 in the MEROPS classification.
[5] It is highly expressed in sexual reproductive structures termed fruiting bodies and has been cloned and characterized at the molecular and functional levels.
The cospin PIC 1 gene sequence isolated from fruiting bodies of the C. cinerea strain AmutBmut can be found under GenBank TM accession number ACX48485.
[6] Cospin a serine protease inhibitor can be of use in various applications ranging from pest management, crop protection to drug development, design for therapeutics, and basic medical research.