The Wood River sculpin (Cottus leiopomus) is a species of freshwater ray-finned fish belonging to the family Cottidae, the typical sculpins.

[1] It is endemic to the Big Wood and Little Wood rivers and their tributaries upstream of Magic Reservoir in Blaine County, Idaho in the United States.

[2] Its habitat is similar to other sculpins: small to medium-sized streams that are cool and have swift currents.

It is a species of concern because of its restricted distribution.

This Cottidae article is a stub.