They experience an annual life cycle marked by summer population blooms,[4] which is likely an adaptive result of the strong seasonal changes in their Mediterranean environment.

Planulae use their small cilia to propel them through the water, eventually settling on a hard sediment on which they develop into their polyp form.

These microorganisms live primarily in the mesoglea and lining of the cnidarian's gastrovascular system, bolstering oxygen production, and remain with the jellyfish for the rest of their lifespans.

Female C. tuberculata are internally fertilized with sperm from the mouth arm appendages of their male counterparts, and after a gestation period, eventually release large numbers of planulae into the water.

Older fried egg jellyfish are distinguished by their physical deterioration; their mesoglea are often delicate with a visibly broken exumbrella and their coloration fades significantly.

These mutualistic microorganisms are also known as zooxanthellae, originating from the dinoflagellate phylum, and they commonly engage in symbiotic relationships with many types of jellyfish.

This mutualistic relationship is so crucial to the Mediterranean jellyfish's growth and survival that the preliminary step of premature medusa formation will not initiate without the presence of zooxanthellae.

They do not demonstrate a very high feeding diversity on the taxonomic level; it has been recorded that anywhere between 69% and 82% of their diet consists of organisms associated with the genus Spiroplasma.

This often results in the removal of thousands of Mediterranean jellies from the waters by coastal officials in the summers by fishing boats or large nets.