Rostainuccio ("little Rostaino") was defeated and captured by Jacopo Orsini at Pereto in Abruzzo in 1369, and Alvito was granted by Ladislaus to Andrea Tomacelli, brother of the Count of Sora and of Pope Boniface IX.
After Giacomo's death the county was expanded by his son Antonio, who acquired Gallinaro, Fontechiari, Arce, Popoli (this from his brother Francesco, who had died heirless), and other lands in the Abruzzo and Valcomino.
Antonio's rule was troubled by the turmoil and succession crises of the Kingdom of Naples in the early 15th century, and he lost his lands repeatedly.
Piergiampaolo soon annexed his brother's Abruzzese lands and, after siding against the new king, Ferdinand I, in the revolt of 1460, captured the territories of Montecassino, Arce, and the fiefs of the Colonna in Abruzzo.
He was able to resist the Neapolitans after the French retreat, but in 1496 Sora fell to Frederick I of Naples, followed in 1496 by Alvito, captured by general Gonzalo de Córdoba.
In 1515, after Pietro had embraced the French cause, Alvito was conferred on the viceroy Ramón (Raimondo) de Cardona, who did not live there but rather administered it through a governor.
In the end Tolomeo obtained full rule in Alvito, receiving the title of Duke in 1606 from Philip III of Spain.