The majority of the route is designated, but not always signed, as County Road 435 (CR 435).

The whole southern section from Vineland to Old Winter Garden Road is four lanes wide (the last section, from Florida's Turnpike to Old Winter Garden Road, was completed in 2005).

On February 9, 1926, the Orange County Board of County Commissioners approved a $7 million bond issue to build a system of paved roads, supplementing the limited network already existing; the voters approved it 993 to 143 on March 23, 1926.

Over the years, plans were made to fill the gap; the most recent continued straight from Old Winter Garden Road across SR 50, north across SR 438 about ¼ mile east of the existing road, and curving back to join the road north of SR 438.

Of note are the bypass around Vineland (the old road is Lake Street and Ruby Lake Road), the realignment at Keene Road south of Apopka (moving it back to the old location next to the Florida Central Railroad, now the West Orange Trail), the realignment just south of Old Winter Garden Road, and the realignment just north of Florida's Turnpike, crossing an arm of Lake Steer.

A while ago, CR 435 signs were installed at the south end, where it meets CR 535 (former SR 535); this section was never SR 435 but may have been state-maintained (along with Good Homes Road).