The road begins at U.S. Route 192 (US 192) in Kissimmee, heading north, ending at Interstate 4 (I-4) at Lake Buena Vista.

SR 535 begins at an intersection with US 192/SR 530 in Kissimmee, Osceola County, heading north on Vineland Road, a six-lane divided highway.

SR 535 heads through dense woods, passing to the west of the Lake Buena Vista Factory Stores before crossing under the SR 417 toll road without an interchange.

The road intersects International Drive before reaching a junction with SR 536 in a commercial area.

Past this intersection, the state road passes through areas of resorts and businesses, curving to the north.