From here, CR 529 heads north as a four-lane undivided road that passes near industrial and commercial development with some homes.

After an intersection of New Durham Road (CR 501), the route runs northwest along the border between Piscataway to the west and South Plainfield to the east as a four-lane undivided road into commercial areas, soon widening into a divided highway at the intersection of Metlars Lane (CR 609).

At this point, the route becomes two-lane Washington Avenue and runs north through residential areas, passing over New Market Pond and Conrail Shared Assets Operations' Lehigh Line on a bridge.

Farther north, the road crosses the intersection of Vail Avenue/West 7th Street (CR 601) before heading into Dunellen.

Following this, CR 529 passes more homes before crossing into Green Brook, Somerset County in a wooded area.