Cowles is a village in Webster County, Nebraska, United States.

[6][7] A post office was established in Cowles in 1879, and remained in operation until it was discontinued in 1960.

[8] According to the United States Census Bureau, the village has a total area of 0.56 square miles (1.45 km2), all land.

There were 13 housing units at an average density of 23.2 per square mile (9.0/km2).

22.2% of all households were made up of individuals, and 11.1% had someone living alone who was 65 years of age or older.

There were 16.7% of families and 43.2% of the population living below the poverty line, including 60.0% of under eighteens and 100.0% of those over 64.