His research interests were in the areas of large-scale computer modeling of the cardiac bidomain and neuroengineering.
[2][3] He continued his studies at Duke and received the Doctor of Philosophy (Ph.D.) degree in biomedical engineering in 1988.
His Ph.D. advisor was Robert Plonsey and his dissertation was titled "Structure and Volume Conductor Effects on Propagation in Cardiac Tissue".
In 2001, he was named the first Medtronics Visiting Professor of Virtual Electrophysiology, in the Department of Cardiology, University of Lausanne, Switzerland.
[5] In 2003, he and Miguel Nicolelis founded and co-directed the Center for Neuroengineering where they developed a Brain Machine Interface in which electrode arrays were implanted into a monkey's brain that were able to detect the monkey's motor intent and thus able to control reaching and grasping movements performed by a robotic arm.