This species is endemic to the Sea of Cortez, ranging from Western Mexico to Ecuador in intertidal zones.

First described in 1834 by George Brettingham Sowerby I, C. incrassata was reclassified by William Swainson as the holotype specimen for the Crassispira genus, but its current taxonomic rank is unclear.

It was first described in 1834 by British conchologist George Brettingham Sowerby I as Pleurotoma incrassata in his report to the Zoological Society of London.

[1][3] In 1958, James Hamilton McLean and Myra Keen proposed that C. incrassata represented a southern variation of C. bottae, but this classification has not been widely adopted.

[10] C. incrassata's shell differs from Crassispira bottae in that it is slightly larger, has a shorter aperture, and the spine tapers off sooner.

The odontophore is medium-sized and made of a single layer of cells that forms a pair of unfused cartilage.

[11] C. incrassata is endemic to the Sea of Cortez, and commonly found from Western Mexico to Ecuador.