Crespina Lorenzana is a comune (municipality) in the Province of Pisa in the Italian region Tuscany.

Crespina Lorenzana borders the following municipalities: Casciana Terme Lari, Cascina, Collesalvetti, Fauglia, Orciano Pisano, Santa Luce.

The municipality is composed by six frazioni (towns and villages): The municipality of Crespina Lorenzana was created on 1 January 2014 by merging the former municipalities of Crespina and Lorenzana.

The municipal seat is in Crespina.

This Province of Pisa location article is a stub.