[2] He made his professional debut in 2021 with the rookie–level Arizona Complex League White Sox, logging a 7.82 ERA with 62 strikeouts over 13 games (12 starts).
[3] Mena began the 2022 campaign with the Single–A Kannapolis Intimidators before later being promoted to the High–A Winston-Salem Dash and Double–A Birmingham Barons.
[7] The White Sox traded Mena to the Arizona Diamondbacks on February 3, 2024, in exchange for Dominic Fletcher.
[10] He made his major league debut the same day against the Los Angeles Dodgers, allowing four runs on four hits with two strikeouts over three innings.
[11] On August 2, it was announced that Mena would likely miss the remainder of the season after suffering a right forearm strain.