Cristofor Segni (1604–1661) was a Roman Catholic prelate who served as Titular Archbishop of Thessalonica (1645–1661).

[2] On 24 April 1645, he was appointed during the papacy of Pope Innocent X as Titular Archbishop of Thessalonica.

[1][2] On 11 February 1646, he was consecrated bishop by Giovanni Giacomo Panciroli, Cardinal-Priest of Santo Stefano al Monte Celio, with Alfonso Gonzaga, Titular Archbishop of Rhodus, and Girolamo Farnese, Titular Archbishop of Patrae, serving as co-consecrators.

[2] He served as Titular Archbishop of Thessalonica until his death on 8 July 1661.

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