Crosshouse railway station was a railway station serving the village of Knockentiber and nearby Crosshouse, East Ayrshire, Scotland.

The station was originally part of the Glasgow, Paisley, Kilmarnock and Ayr Railway.

[1] Busby station had a short life and closed on 15 April 1850,[1] however the station reopened as Crosshouse (then as part of the Glasgow and South Western Railway) on 1 September 1872.

[1] Crosshouse and its four platforms served as a junction station, allowing travel to Kilmarnock from the directions of both Irvine and Dalry.

[2] The Irvine service was withdrawn on 6 April 1964,[3] with the station closing permanently to passengers on 18 April 1966,[4] although the line was still in use by freight trains and diverted passenger trains until 23 October 1973.