In this city lived, during the government of Dr. Francia, the founder and first dictator of Paraguay, in his exile for over 30 years, José Gervasio Artigas, the liberator of Uruguay.

During the War against the Triple Alliance, the Marshall López declared Curuguaty as his last and the 4th capital of Paraguay and the Vice-President Domingo Francisco Sánchez Corvalán settled in the place.

López settled his troops near Curuguaty on the banks of the Itandey Stream, when he was going towards the Amambay Cordillera, where the last battles would be fought during the war.

Since the early years of the new millennium landless peasants fight for their land, which was in part at least given in the past decades to influential and wealthy men and women of the political upper classes of Paraguay.

Reaching the city, a not paved detour to the left leads to Villa Ygatimí, Ypehú, Itanará and the Mbaracayú Forest National Reserve.