Cypress Creek Middle High School was established in 2017 in Wesley Chapel, Florida and was built to accommodate increasing enrollment and relieve overcrowding in the fast-growing area.

[5] Students from four other high schools were rezoned to attend the new Cypress Creek, and adjustments were made to other boundaries.

[10] The school offers Advanced Placement classes, as well as course specialties, termed "Academies", in such subjects as Criminal Justice, where students are introduced to law, forensics, patrol enforcement, and self-defense techniques.

[16] It now has a full varsity sports program, including football, soccer, basketball for both boys and girls, track and field, swimming, tennis, golf and baseball.

[17] A 2,273 sq ft (211 m2) weight room is part of the facility, alongside the county's only rubberized track;[16][15] the nickname is the Coyotes.