He enjoyed the patronage of Eugenius IV, who had been Papal legate in the March of Ancona from 1420 to 1422, Cosimo de' Medici, and the Visconti of Milan.
[7] On 5 April 1436, he described and sketched a plan of the ancient city walls, indicating the position of the theatre and the fortifications of the acropolis and mentioning the existence of inscriptions.
Pushed by a strong curiosity, he also bought a great number of documents which he used to write six volumes of Commentarii ("Commentaries").
The ravages of time have been unkind to Cyriacus's lifework, which he never published, but which fortunately circulated in manuscript and in copies of his drawings; the Commentarii were lost in the 1514 fire of the library of Alessandro Sforza and Costanza Varano in Pesaro.
[8] Long after his death, some surviving texts were printed: Epigrammata reperta per Illyricum a Kyriaco Anconitano (Rome, 1664), Cyriaci Anconitani nova fragmenta notis illustrata, (Pesaro, 1763) and Itinerarium (Florence, 1742).