The Czech Republic competed at the 2020 Summer Paralympics in Tokyo, Japan, from 24 August to 5 September 2021.

[1][2][3] Tereza Brandtlová, David Drahonínský, Václav Košťál and Šárka Musilová have all qualified to compete.

Eva Datinská, Michal Enge, Tereza Jakschová, Aleš Kisý, Anna Luxová and František Serbus have all qualified to compete.

Kateřina Antošová, Patrik Jahoda, Ivo Koblasa and Tomáš Mošnička have all qualified to compete.

[6] Czech Republic entered one athletes into the table tennis competition at the games.