2BYG, 2HE2174023859ENSG00000150672ENSMUSG00000052572Q15700Q91XM9NM_001364NM_001351274NM_001351275NM_001351276NM_001377966NM_001377967NM_001377968NM_001377970NM_001377971NM_001377972NM_001377973NM_001377974NM_001377975NM_001377976NM_001377977NM_001377978NM_001377979NM_001377980NM_001377981NM_001377982NM_001377983NM_175892NM_001243046NM_001243047NM_011807NP_001355NP_001338203NP_001338204NP_001338205NP_001364895NP_001364896NP_001364897NP_001364899NP_001364900NP_001364901NP_001364902NP_001364903NP_001364904NP_001364905NP_001364906NP_001364907NP_001364908NP_001364909NP_001364910NP_001364911NP_001364912NP_001229975NP_001229976NP_035937Disks large homolog 2 (DLG2) also known as channel-associated protein of synapse-110 (chapsyn-110) or postsynaptic density protein 93 (PSD-93) is a protein that in humans is encoded by the DLG2 gene.
[5][6] Chapsyn-110/PSD-93 a member of the membrane-associated guanylate kinase (MAGUK) family.
The protein forms a heterodimer with a related family member that may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, ion channels, and associated signaling proteins.
Alternatively spliced transcript variants encoding distinct isoforms have been described but their full-length nature has yet to be completely determined.
[7] DLG2 has been shown to interact with GRIN2B,[8][9] KCNJ12.