[6] In humans, the gene is located on the long arm of chromosome 20 (20q13.33) on the Watson (positive strand).

The gene is 40,867 bases in length and the encoded protein has 198 amino acids with a predicted molecular weight of 22.149 kilodaltons (kDa).

[10] CSPα plays a role in membrane trafficking and protein folding, and has been shown to have anti-neurodegenerative properties.

[13] CSP interacts with the calcium sensor protein synaptotagmin 9 via its linker domain.

[14] Huntingtin-interacting protein 14, a palmitoyl transferase, is required for exocytosis and targeting of CSP to synaptic vesicles.

[15] The rat CSP forms a complex with Sgt (SGTA) and Hsc70 (HSPA8) located on the synaptic vesicle surface.