4XVI, 4XVK, 4XVL, 4XVM353497272158ENSG00000130997ENSMUSG00000045102Q7Z5Q5Q7TQ07NM_181808NM_001289803NM_001289804NM_181857NP_861524NP_001276732NP_001276733NP_862905Polymerase (DNA directed) nu is a protein in humans that is encoded by the POLN gene.

[5] It is a family A DNA polymerase,[6] considered to be the least effective of the polymerase enzymes.

[7] However, DNA polymerase nu plays an active role in homology repair during cellular responses to crosslinks, fulfilling its role in a complex with helicase.

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