Da Boom

The episode featured guest performances by Patrick Duffy, Victoria Principal, Jack Perkins, Will Sasso, and Joey Slotnick along with several recurring voice actors for the series.

This is the first episode that aired to feature Mila Kunis as the voice of Meg Griffin, following Lacey Chabert's departure from the series.

This causes a worldwide nuclear attack, with vehicles crashing and missiles self-launching, destroying much of the world, and mutating, injuring, or killing most of its inhabitants.

Realizing that their route to Natick was all for nothing, Stewie berates Peter for costing them their lives before tripping and falling into a puddle of nuclear waste; his arms soon mutate into tentacles.

He proceeds to bring out the plan of making guns, but Cleveland doesn't desire to agree with it, stating it could be a problem.

In a live action epilogue, which serves as a parody of Dallas, the events of the episode are revealed to have been a dream experienced by Pam Ewing (Victoria Principal).

[4] Lacey Chabert, the original voice of Meg, left the series due to time constraints with her acting role in Party of Five, as well as schoolwork.

[5] Kunis won the role after auditions and a slight rewrite of the character, in part due to her performance on That '70s Show.

[7] This has become a running gag, having reappeared in episodes such as "Blind Ambition", "Internal Affairs",[8] "No Chris Left Behind"[9] and "Meet the Quagmires".

Recurring guest voice actress Lori Alan, writer Danny Smith, and actor Patrick Warburton also made minor appearances.

[2] The episode's live-action epilogue is a reference to the final (moments and) episode "Blast From the Past" of season 9 of the CBS soap opera Dallas that erased the death of Bobby Ewing (Patrick Duffy), which turned out to be a dream experience by Pamela Ewing (Victoria Principal).

Principal and Duffy reprised their respective Dallas roles in a live-action recreation of the shower scene at the end of the episode.

Arriving at the Twinkie factory, Peter uses the same words to describe what he sees that Dr. Ellie Arroway used in Contact when witnessing a celestial event in a foreign galaxy.