A variant has been described that has large, angular pores similar to those in the genus Trametes, named F. quercina forma trametea.

It has also been reported in Northern Africa, North America, (Tunisia), Asia from Caucasus to India, and also Australia.

[9] Fruit bodies of Fomitopsis quercina have been used as a natural comb and aphrodisiac, employed for brushing down horses with tender skin.

[12] The lignin-degrading enzyme laccase, isolated and purified from F. quercina, has shown use in biodegrading a variety of toxic dyes and pigments.

[13] The compound quercinol (a chromene derivative), isolated from the oak mazegill, has anti-inflammatory activity, and inhibits the enzymes cyclooxygenase-2, xanthine oxidase, and horseradish peroxidase.