[1][2] Tsuji is best known for his performance as Jin Sakai in the video game Ghost of Tsushima (2020) and as the Crown Prince in the TV series The Man in the High Castle (2015–2019).

Tsuji worked at The Coffee Bean & Tea Leaf in The Grove at Farmers Market in Los Angeles.

In 2009, Tsuji wrote and directed Monkey Madness, which was produced by The Los Angeles Theatre Ensemble.

He did voice acting for the video games Call of Duty: Black Ops 4 (2018) and Prey: Mooncrash (2018).

In 2019, he won the Los Angeles Drama Critics Circle Award for Outstanding Featured Performance in Cambodian Rock Band at South Coast Rep!.