[2] He received his Bachelor of Arts in political philosophy, summa cum laude, from Princeton University in 1999 with membership in Phi Beta Kappa and his Juris Doctor from Yale Law School in 2005.

[7] In 2019, Ho was one of five ACLU lawyers featured in the documentary The Fight, produced by actress Kerry Washington, which followed his preparation, oral argument, and reaction in the United States Supreme Court proceedings around Department of Commerce v. New York.

[8] In 2018, Ho was a lead attorney in Fish v. Kobach, in which the district court ruled that it was illegal to require documentary proof of citizenship in order to register to vote.

In Department of Commerce v. New York (2019), Ho represented a coalition of immigrant advocacy groups who successfully challenged Donald Trump's plan to include a citizenship question on the 2020 United States census questionnaire.

[17] During his confirmation hearing, Ho apologized for his "overheated rhetoric" on social media, which included past tweets critical of three Republican members of the Senate Judiciary Committee, Marsha Blackburn, Mike Lee, and Tom Cotton.

[29][30][31] Ho is only the second ACLU lawyer to be confirmed directly to the federal bench as an Article III judge after Ruth Bader Ginsburg.