Its principal performing venue is the Morton H. Meyerson Symphony Center in the Arts District of downtown Dallas.

It continued to perform and grow in numbers and stature, so that in 1945 it was in a position to appoint Antal Doráti as music director.

Several times during the history of the orchestra it has suspended operations, including periods during the First and Second World Wars from 1914 to 1918 and from 1942 to 1945, and more recently in 1974 due to fiscal restraints.

In 2007, Jaap van Zweden was named the DSO's 15th music director, and began his tenure in the 2008–2009 season with an initial contract of four years.

[9] In May 2023, the orchestra announced the appointment of Enrico Lopez-Yañez as Principal Conductor of the Dallas Symphony Presents[10] and Anthony Blake Clark as the new Chorus Director.