Damachava (Belarusian: Дамачава, romanized: Damačava;[a] Russian: Домачево, romanized: Domachevo; Polish: Domaczewo) is an urban-type settlement in Brest District, Brest Region, Belarus.

[1] Within the Grand Duchy of Lithuania, Damachava was part of Brest Litovsk Voivodeship.

In September 1939, Damachava was occupied by the Red Army and, on 14 November 1939, incorporated into the Byelorussian SSR.

From 21 June 1941 until 23 July 1944, Damachava was occupied by Nazi Germany and administered as a part of the Generalbezirk Wolhynien-Podolien of Reichskommissariat Ukraine.

The majority of the town inhabitants were Jewish before World War II.