Damien Jefferson (born October 3, 1997) is an American professional basketball player who last played for Karşıyaka Basket of the Basketbol Süper Ligi (BSL) and the Champions League.

As a senior, he averaged 26.1 points and 8.1 rebounds per game and was named The Times of Northwest Indiana Player of the Year.

[1] Jefferson led his team to a Class 4A sectional title and was named an Indiana All-Star.

[4] As a sophomore, Jefferson averaged 6.2 points and four rebounds per game before his season was cut short due to a high ankle sprain injury.

Jefferson declared for the 2021 NBA draft, forgoing an additional season of eligibility the NCAA granted due to the COVID-19 pandemic.