After graduating from Dr. Phillips High School in Orlando, Florida, Wilkins enrolled at North Carolina State University.

Two years into a quick and promising start to his NCAA career at North Carolina State, Wilkins entered the 2001 NBA draft but decided to withdraw and transfer to University of Georgia.

Diligence in the weight room helped Wilkins have a big summer league and shine in preseason action for the Sonics, allowing him to make the team.

He proved himself in the 2005 Playoffs when injuries struck again, finishing with 15 points, six rebounds and five steals in the Sonics' Game 4 win over San Antonio.

[6] A restricted free agent in the summer of 2005, Wilkins received an offer from the Minnesota Timberwolves in August 2005,[7] which the Sonics matched within 7 days.

[9] On July 27, 2009, Wilkins was traded to the Minnesota Timberwolves along with Chucky Atkins for center Etan Thomas and two future second-round draft picks.

[25] After initially signing with a Venezuelan team for the 2015–16 season, Wilkins was swayed into re-entering the NBA following the injury to Michael Kidd-Gilchrist of the Charlotte Hornets.

[34] Wilkins represented the United States national team at the 2015 Pan American Games, where he won a bronze medal.