She is the co-founder of Vital Space, a non-profit organisation is based upon the principle that artworks can change the world for the better[1] and "dedicated to the initiation of art projects designed to reach and influence a wide and diverse audience.

[citation needed] Stratou represented Greece at the 48th Venice Biennale in 1999 (the first woman in 30 years to do so), and the Adelaide Festival in Australia in 2012.

[4][5] For the 2004 Olympics in Athens, her piece The River of Life at the National Museum of Contemporary Art was a part of the Transcultures project.

It showed seven videos on seven large screens in a circular room; the films were shot over ten months of seven major rivers from sunrise to sunset with the camera fixed in the same position to capture the uninterrupted flow and shared rhythm.

Her mother is Eleni Potaga-Stratou, a Greek modern artist, and her father is Phaidron Stratos from the Stratos family, who founded the Peiraiki-Patraiki textile industry in Patras, Peloponnese, at one time Greece’s largest textile industry.