In more recent years, the Appleton-Parker House has attracted attention as the one-time home of former General Electric CEO Jack Welch and for having been listed on a number of occasions with a considerable asking price.

In part thanks to his established reputation following Willard's completion of the Bunker Hill Monument, Parker wrote specifically of his confidence in the architect in a letter to John Collins Warren dated October 8, 1825.

[8] On February 10, 1818, Parker, Patrick Tracy Jackson, and other members of the Boston Associates, were granted the charter of the Suffolk Bank by the Massachusetts General Court.

[9] Daniel Parker was recorded in the Acts and Resolves passed by the General Court section of the Private and Special Statutes of the Commonwealth of Massachusetts of 1822 as incorporating the Mashapog Turnpike Corporation "... for the purpose of locating, making and keeping in good repair, a turnpike road, from Norton meeting-house, in the county of Bristol, to the third school house, (so called) in the town of Canton, in the county of Norfolk, on the most direct and convenient route ...."[10] As of 1831 Parker's various business roles included: Director of the Office of Discount and Deposit Boston branch of the Bank of the United States, Director of the Columbian Insurance Company, Director of the Massachusetts Hospital Life Insurance Company, along with his friends Samuel Appleton and Nathan Appleton, and as Trustee of Provident Institution for Savings in the Town of Boston.

[11] Amongst Daniel Parker's closest friends and colleagues, many of them the Boston's most established and successful businessmen and public servants, was the Chief Justice of the Massachusetts Supreme Court, Lemeul Shaw.

[17] Parker was also one of a number of patrons and trustees that contributed to the commission of the first painting to join the Atheneum's collection; a portrait of the organizations benefactor James Perkins by Gilbert Stuart.

[20] Daniel P. Parker's wife, Mary Weekes, also held her own prominent position as president of the Fragment Society, the oldest continuous sewing circle in Boston's history, in the years 1838, 1849, 1850, and 1852.

[21] Even in the year of his death, 1850, Parker continued his philanthropic endeavors, contributing to the purchase of protective casing for and cataloging of the George Washington Library at the Boston Athenaeum.

[22] Following “a painful illness of several months”, Daniel Pinckney Parker died at his home on Beacon Street on August 31, 1850, one day after his sixty-ninth birthday.